{"id":64861,"date":"2026-07-16T15:23:00","date_gmt":"2026-07-16T08:23:00","guid":{"rendered":"https:\/\/thaipropertynews.com\/feeds\/?p=64861"},"modified":"2026-07-16T15:23:00","modified_gmt":"2026-07-16T08:23:00","slug":"scie-study-shows-hilo-wave-promotes-regenerative-skin-remodeling-without-inflammatory-response","status":"publish","type":"post","link":"https:\/\/thaipropertynews.com\/feeds\/?p=64861","title":{"rendered":"SCIE Study Shows HILO WAVE\u00ae Promotes Regenerative Skin Remodeling Without Inflammatory Response"},"content":{"rendered":"

Peer-reviewed preclinical findings validate the regenerative mechanism of HILO WAVE\u00ae’s proprietary Dual-HA Technology (DHC\u00ae).<\/span><\/i><\/b><\/p>\n

SEOUL, South Korea<\/span>, July 16, 2026<\/span> \/PRNewswire\/ — HILO WAVE\u00ae, HIGHER Corporation’s proprietary Dual-HA Collagen Booster, has further strengthened its scientific evidence with the publication of a preclinical study in the International Journal of Molecular Sciences<\/i> (IJMS), an SCIE-indexed international scientific journal.<\/p>\n

\n

\"\"<\/a>
<\/span><\/p>\n<\/div>\n

Developed for regenerative aesthetic medicine, HILO WAVE\u00ae<\/span>\u00a0is designed to improve skin quality and support natural-looking volumization through regenerative biostimulation.<\/p>\n

The product is powered by HIGHER Corporation’s proprietary Dual Hyaluronic Acid Complex (DHC\u00ae), which combines high- and low-molecular-weight hyaluronic acid to promote skin regeneration while minimizing inflammatory responses.<\/p>\n

The published study, titled “<\/b>Regenerative Skin Remodeling by a Dual Hyaluronic Acid Hybrid Complex in Multimodal Preclinical Models,” was conducted through an international collaborative research project led by the Department of Dermatology at Yonsei University Severance Hospital.<\/p>\n

Unlike conventional collagen biostimulatory approaches that rely on localized inflammatory responses, the study investigated the biological mechanism of DHC\u00ae and its ability to support regenerative skin remodeling through a biomaterial-based approach.<\/p>\n

The preclinical findings demonstrated stable fibroblast viability, increased extracellular matrix (ECM) activity, enhanced antioxidant capacity, and improvements in skin barrier-related markers. In addition, no significant inflammatory responses were observed in animal models, supporting the favorable biological safety profile of DHC\u00ae.<\/p>\n

The findings suggest that DHC\u00ae promotes collagen synthesis and tissue regeneration by regulating the skin microenvironment while minimizing unnecessary inflammation, providing scientific evidence for the regenerative mechanism of HILO WAVE\u00ae<\/span>.<\/p>\n

“This publication represents another important step in building the scientific foundation of HILO WAVE\u00ae<\/span>,”<\/i> said a spokesperson for HIGHER Corporation. “As physicians increasingly seek evidence-based treatment options, we remain committed to generating high-quality scientific and clinical evidence that supports the safety, mechanism, and clinical value of our proprietary Dual-HA Technology.”<\/i><\/p>\n

Building on this foundation<\/span>, HIGHER Corporation will host the\u00a0HILO WAVE\u00ae Global Webinar on August 12, 2026, featuring evidence-based treatment protocols, live treatment demonstrations<\/span>, and an interactive Q&A with Dr.\u00a0Kyung Tae Bae.<\/p>\n

Registration is open to licensed healthcare professionals.<\/span><\/p>\n

For more information and registration, please visit:
https:\/\/higher-webinar.com\/<\/b><\/a><\/p>\n

About HIGHER Corporation<\/b><\/p>\n

HIGHER Corporation is a South Korea-based medical aesthetics company dedicated to advancing regenerative aesthetic medicine through proprietary technology, scientific research, and physician education. The company develops innovative aesthetic solutions while supporting evidence-based clinical practice through international educational initiatives.<\/p>\n

For more information, visit https:\/\/www.highercorp.co.kr\/<\/a><\/p>","protected":false},"excerpt":{"rendered":"

<\/p>\n

Peer-reviewed preclinical findings validate the regenerative mechanism of HILO WAVE\u00ae’s proprietary Dual-HA Technology (DHC\u00ae).<\/span><\/i><\/b><\/p>\n

SEOUL, South Korea<\/span>, July 16, 2026<\/span> \/PRNewswire\/ — HILO WAVE\u00ae, HIGHER Corporation’s proprietary Dual-HA Collagen Booster, has further strengthened its scientific evidence with the publication of a preclinical study in the International Journal of Molecular Sciences<\/i> (IJMS), an SCIE-indexed international scientific journal.<\/p>\n

\n

\"\"<\/a>
<\/span><\/p>\n<\/div>\n

Developed for regenerative aesthetic medicine, HILO WAVE\u00ae<\/span>\u00a0is designed to improve skin quality and support natural-looking volumization through regenerative biostimulation.<\/p>\n

The product is powered by HIGHER Corporation’s proprietary Dual Hyaluronic Acid Complex (DHC\u00ae), which combines high- and low-molecular-weight hyaluronic acid to promote skin regeneration while minimizing inflammatory responses.<\/p>\n

The published study, titled “<\/b>Regenerative Skin Remodeling by a Dual Hyaluronic Acid Hybrid Complex in Multimodal Preclinical Models,” was conducted through an international collaborative research project led by the Department of Dermatology at Yonsei University Severance Hospital.<\/p>\n

Unlike conventional collagen biostimulatory approaches that rely on localized inflammatory responses, the study investigated the biological mechanism of DHC\u00ae and its ability to support regenerative skin remodeling through a biomaterial-based approach.<\/p>\n

The preclinical findings demonstrated stable fibroblast viability, increased extracellular matrix (ECM) activity, enhanced antioxidant capacity, and improvements in skin barrier-related markers. In addition, no significant inflammatory responses were observed in animal models, supporting the favorable biological safety profile of DHC\u00ae.<\/p>\n

The findings suggest that DHC\u00ae promotes collagen synthesis and tissue regeneration by regulating the skin microenvironment while minimizing unnecessary inflammation, providing scientific evidence for the regenerative mechanism of HILO WAVE\u00ae<\/span>.<\/p>\n

“This publication represents another important step in building the scientific foundation of HILO WAVE\u00ae<\/span>,”<\/i> said a spokesperson for HIGHER Corporation. “As physicians increasingly seek evidence-based treatment options, we remain committed to generating high-quality scientific and clinical evidence that supports the safety, mechanism, and clinical value of our proprietary Dual-HA Technology.”<\/i><\/p>\n

Building on this foundation<\/span>, HIGHER Corporation will host the\u00a0HILO WAVE\u00ae Global Webinar on August 12, 2026, featuring evidence-based treatment protocols, live treatment demonstrations<\/span>, and an interactive Q&A with Dr.\u00a0Kyung Tae Bae.<\/p>\n

Registration is open to licensed healthcare professionals.<\/span><\/p>\n

For more information and registration, please visit:
https:\/\/higher-webinar.com\/<\/b><\/a><\/p>\n

About HIGHER Corporation<\/b><\/p>\n

HIGHER Corporation is a South Korea-based medical aesthetics company dedicated to advancing regenerative aesthetic medicine through proprietary technology, scientific research, and physician education. The company develops innovative aesthetic solutions while supporting evidence-based clinical practice through international educational initiatives.<\/p>\n

For more information, visit https:\/\/www.highercorp.co.kr\/<\/a><\/p>\n

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