{"id":31597,"date":"2025-09-04T14:09:09","date_gmt":"2025-09-04T14:09:09","guid":{"rendered":"https:\/\/www.hotelsalepage.com\/feed\/cision-pr-newswire\/accro-bioscience-to-present-phase-ii-data-of-ac-201-for-plaque-psoriasis-at-the-european-academy-of-dermatology-venereology-congress-2025-in-paris\/"},"modified":"2025-09-04T14:09:09","modified_gmt":"2025-09-04T14:09:09","slug":"accro-bioscience-to-present-phase-ii-data-of-ac-201-for-plaque-psoriasis-at-the-european-academy-of-dermatology-venereology-congress-2025-in-paris","status":"publish","type":"post","link":"https:\/\/thaipropertynews.com\/feeds\/?p=31597","title":{"rendered":"Accro Bioscience to Present Phase II Data of AC-201 for Plaque Psoriasis at the European Academy of Dermatology &amp; Venereology Congress 2025 in Paris"},"content":{"rendered":"<p><span class=\"legendSpanClass\"><span class=\"xn-location\">NEW YORK<\/span> and SUZHOU, <span class=\"xn-location\">China<\/span><\/span>, <span class=\"legendSpanClass\"><span class=\"xn-chron\">Sept. 4, 2025<\/span><\/span> \/PRNewswire\/ &#8212; Accro Bioscience (Accropeutics), a clinical-stage biotech company focused on molecular mechanisms of regulated cell death and related pathogenesis in human diseases, today\u00a0announced that it will present results from a Phase II clinical study evaluating AC-201, an oral, selective TYK2\/JAK1 Inhibitor, in moderate-to-severe plaque psoriasis, at the European Academy of Dermatology &amp; Venereology (EADV) Congress, being held <span class=\"xn-chron\">September 17-20<\/span><sup>th<\/sup>, in <span class=\"xn-location\">Paris<\/span>.<\/p>\n<p><b>Details of the presentation are as follows:<br \/><\/b><b>Abstract Type:<\/b> Oral Presentation in the Late Breaking Sessions<br \/><b>Abstract ID:<\/b> LBA-5<br \/><b>Abstract Title:<\/b> Efficacy and Safety of a Selective Oral TYK2\/JAK1 Inhibitor, AC-201, in Patients with Plaque Psoriasis: A Phase II, Randomized, Double-blinded, Placebo-Controlled Trial<br \/><b>Session Title:<\/b> D3T01.4F<br \/><b>Session Room:<\/b> <span class=\"xn-person\">Paris Nord<\/span><br \/><b>Presentation Time:<\/b> 17:15 &#8211; 17:30 Friday, 19 September<\/p>\n<p><b>About AC-201<\/b><\/p>\n<p>AC-201\u00a0is a novel, highly selective and potent oral small-molecule inhibitor of TYK2\/JAK1 that binds to the pseudo kinase domain (JH2) of TYK2\/JAK1, with minimal effect on the JAK2\/JAK2 signaling pathway. It\u00a0is currently being developed to treat immune mediated inflammatory diseases such as psoriasis (PsO),\u00a0non-infectious uveitis (NIU), and cutaneous lupus erythematosus (CLE). Phase 1 studies in healthy volunteers conducted in <span class=\"xn-location\">Australia<\/span> and <span class=\"xn-location\">China<\/span> demonstrated that AC-201 was generally safe and well-tolerated across all dose groups, with no adverse events (AEs) leading to discontinuation or serious adverse events (SAEs).<\/p>\n<p><b>About Accro Bioscience<\/b><\/p>\n<p>Accro Bioscience is a clinical-stage biotech company with a core focus on the molecular mechanisms of regulated cell death and related pathogenesis in human diseases. The company currently has three clinical-stage assets. AC-201, a selective TYK2\/JAK1 inhibitor with therapeutic potential across a broad range of immune mediated inflammatory diseases, has completed a Phase 2 clinical trial in psoriasis with positive efficacy and safety readout. The RIPK2 inhibitor, AC-101, has completed the Phase 1 study in <span class=\"xn-location\">Australia<\/span> and <span class=\"xn-location\">China<\/span> with excellent safety and PK\/PD data, and a Ph1b trial in UC patients is currently ongoing. The RIPK1 inhibitor, AC-003, obtained Orphan Drug Designation from the FDA, has completed the Phase 1 study in <span class=\"xn-location\">China<\/span> and <span class=\"xn-location\">the United States<\/span>, and is currently in a Phase <span class=\"xn-money\">1b<\/span> trial for the treatment of aGvHD patients. Accro Bioscience owns global rights of the assets with 25 patents issued in <span class=\"xn-location\">China<\/span>, <span class=\"xn-location\">Japan<\/span>, US, Korea and EU.<\/p>\n<p>Media Contact:<br \/><span class=\"xn-person\">Jack Xu<\/span><br \/>Accro Bioscience<br \/><a href=\"mailto:Info@accropeutics.com\" target=\"_blank\" rel=\"nofollow\">Info@accropeutics.com<\/a>\u00a0<\/p>","protected":false},"excerpt":{"rendered":"<p><!-- wp:html --><\/p>\n<p><span class=\"legendSpanClass\"><span class=\"xn-location\">NEW YORK<\/span> and SUZHOU, <span class=\"xn-location\">China<\/span><\/span>, <span class=\"legendSpanClass\"><span class=\"xn-chron\">Sept. 4, 2025<\/span><\/span> \/PRNewswire\/ &#8212; Accro Bioscience (Accropeutics), a clinical-stage biotech company focused on molecular mechanisms of regulated cell death and related pathogenesis in human diseases, today\u00a0announced that it will present results from a Phase II clinical study evaluating AC-201, an oral, selective TYK2\/JAK1 Inhibitor, in moderate-to-severe plaque psoriasis, at the European Academy of Dermatology &amp; Venereology (EADV) Congress, being held <span class=\"xn-chron\">September 17-20<\/span><sup>th<\/sup>, in <span class=\"xn-location\">Paris<\/span>.<\/p>\n<p><b>Details of the presentation are as follows:<br \/><\/b><b>Abstract Type:<\/b> Oral Presentation in the Late Breaking Sessions<br \/><b>Abstract ID:<\/b> LBA-5<br \/><b>Abstract Title:<\/b> Efficacy and Safety of a Selective Oral TYK2\/JAK1 Inhibitor, AC-201, in Patients with Plaque Psoriasis: A Phase II, Randomized, Double-blinded, Placebo-Controlled Trial<br \/><b>Session Title:<\/b> D3T01.4F<br \/><b>Session Room:<\/b> <span class=\"xn-person\">Paris Nord<\/span><br \/><b>Presentation Time:<\/b> 17:15 &#8211; 17:30 Friday, 19 September<\/p>\n<p><b>About AC-201<\/b><\/p>\n<p>AC-201\u00a0is a novel, highly selective and potent oral small-molecule inhibitor of TYK2\/JAK1 that binds to the pseudo kinase domain (JH2) of TYK2\/JAK1, with minimal effect on the JAK2\/JAK2 signaling pathway. It\u00a0is currently being developed to treat immune mediated inflammatory diseases such as psoriasis (PsO),\u00a0non-infectious uveitis (NIU), and cutaneous lupus erythematosus (CLE). Phase 1 studies in healthy volunteers conducted in <span class=\"xn-location\">Australia<\/span> and <span class=\"xn-location\">China<\/span> demonstrated that AC-201 was generally safe and well-tolerated across all dose groups, with no adverse events (AEs) leading to discontinuation or serious adverse events (SAEs).<\/p>\n<p><b>About Accro Bioscience<\/b><\/p>\n<p>Accro Bioscience is a clinical-stage biotech company with a core focus on the molecular mechanisms of regulated cell death and related pathogenesis in human diseases. The company currently has three clinical-stage assets. AC-201, a selective TYK2\/JAK1 inhibitor with therapeutic potential across a broad range of immune mediated inflammatory diseases, has completed a Phase 2 clinical trial in psoriasis with positive efficacy and safety readout. The RIPK2 inhibitor, AC-101, has completed the Phase 1 study in <span class=\"xn-location\">Australia<\/span> and <span class=\"xn-location\">China<\/span> with excellent safety and PK\/PD data, and a Ph1b trial in UC patients is currently ongoing. The RIPK1 inhibitor, AC-003, obtained Orphan Drug Designation from the FDA, has completed the Phase 1 study in <span class=\"xn-location\">China<\/span> and <span class=\"xn-location\">the United States<\/span>, and is currently in a Phase <span class=\"xn-money\">1b<\/span> trial for the treatment of aGvHD patients. Accro Bioscience owns global rights of the assets with 25 patents issued in <span class=\"xn-location\">China<\/span>, <span class=\"xn-location\">Japan<\/span>, US, Korea and EU.<\/p>\n<p>Media Contact:<br \/><span class=\"xn-person\">Jack Xu<\/span><br \/>Accro Bioscience<br \/><a href=\"mailto:Info@accropeutics.com\" target=\"_blank\" rel=\"nofollow\">Info@accropeutics.com<\/a>\u00a0<\/p>\n<p><!-- \/wp:html --><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":[],"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[5,7],"tags":[],"class_list":["post-31597","post","type-post","status-publish","format-standard","hentry","category-cision-pr-newswire","category-cision-pr-newswire-en"],"_links":{"self":[{"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=\/wp\/v2\/posts\/31597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31597"}],"version-history":[{"count":0,"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=\/wp\/v2\/posts\/31597\/revisions"}],"wp:attachment":[{"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31597"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thaipropertynews.com\/feeds\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}